Thanks for the question! It’s generally not safe to assume anything on the LSAT! Opinions in prompts are probably slightly more likely to be conclusions, but I don’t even know if that’s true. It’s definitely not true that opinions can’t be premises. Take the following example:
P: Cheating on tests is wrong. P: Bob cheated on his math test. C: Bob did something wrong.
The first premise, “cheating on tests is wrong,” can easily be classified as an opinion.
Now, even if it’s the only opinion that doesn’t seem to support any other statements, you can’t assume it’s the conclusion. Why? Because it could be the conclusion, or it could just be background info. Remember, sometimes the LSAT will put in random background information that doesn’t end up figuring into a premise. So an opinion could end up filling that role as well.
Hope this helps! Feel free to ask any other questions that you might have.